James Roguski
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https://rumble.com/v5yd7lz-breaking-jab-white-clot-mystery-solved.html?start=603s
https://johninengland.substack.com/p/tis-mystery-all
Fibrin amyloid microclots represent a novel and potentially important target for both the understanding and treatment of Long COVID and related disorders.
Swedish researchers have found that the SARS-CoV-2 spike protein contains seven distinct peptide regions that form amyloids when incubated at [normal body temperature] 37 degrees C. When the spike protein is exposed to NE (neutrophil enzyme) the enzyme cleaves the spike protein exposing the peptides that are amyloidogenic, and amyloids are generated within 24 hours.
The researchers found that sequences 192–211, 601–620, 1166–1185 were particularly amyloidogenic. Neutrophil enzyme is excreted at the site of ANY infection, or inflammation, making the vaccinated vulnerable to amyloid formation following either of these.
Spike Protein + Neutrophil enzyme → cleavage of spike → exposure of amyloidogenic sequences → formation of fibrils + amyloids
https://pubs.acs.org/doi/10.1021/jacs.2c03925
https://pubmed.ncbi.nlm.nih.gov/35579205/
It is well known that many illnesses, such as Alzheimer’s, are preceded by a process where the body cuts up large proteins into smaller pieces, which can in turn produce the harmful amyloid. In their study, the researchers show that an enzyme from immune system’s white blood cells can cut up coronavirus’ spike protein. When the spike protein is cut up, it produces the exact piece of protein which, according to the researchers’ analysis, is most likely to produce amyloid. This enzyme is released in large quantities from one type of white blood cells, neutrophils, which are released early on during infections such as COVID-19. When the researchers mixed pure spike protein with this enzyme, called neutrophil elastase, unusual fibrils were produced.
We identified two peptides from the SARSCoV-2 proteome that self-assemble into amyloid assemblies. Furthermore, these amyloids were shown to be highly toxic to neuronal cells. We suggest that cytotoxic aggregates of SARS-CoV-2 proteins may trigger neurological symptoms in COVID-19.
Abnormal clots looked a bit like half cooked spaghetti and referred to as dense matted deposits resulting from fibrin polymerization.
These deposits could be induced by things like un-liganded iron, and later, we discovered, also by very low concentrations of bacterial cell wall components.
“We used a special stain (thioflavin T) that only fluoresces when these deposits adopted amyloid-like structures which reflect structural changes in the 3-dimentional structure (but not the primary sequence) of the proteins. We found that this was happening in a variety of chronic inflammatory diseases, such as Alzheimer disease or Parkinson disease. For example, when we added thrombin to a blood sample from someone with asthma, it induced clotting into the amyloid form that bound our fluorogenic stain and then fluoresced.
In acute COVID-19 and Long COVID, they found that no thrombin was needed to start the fibrinogen amyloid microclot process because the SARS-CoV-2 Spike protein was capable of starting the microclot process.
The general principle is that if you acquire a scientific understanding of what’s gone wrong with a disease, you can use that knowledge to fix it. I think we have now acquired a scientific understanding of a key element of what in particular has gone wrong in COVID-19 and in Long COVID. These microclots are the central element to everything. If you’ve got these microclots, they block up the microcapillaries, preventing red blood cells from going through so oxygen doesn’t get to the tissues. The tissues that have been blocked from getting oxygen are the ones that are going to manifest disease.
The microclots account for all the obvious symptoms like fatigue, where patients are gasping for oxygen. We think that a lot of sequelae is caused by microclots that lead to a variety of problems, not only due directly to hypoxia, but also ischemia reperfusion injury, which causes so-called post-exertional malaise. You’ve got to break the cycle somewhere and the easy place to break it is the microclots because they’re really the chief bad guys.
Douglas B. Kell, CBE, DSc, MA, DPhil, FAAAS, FLSW, FSB, of the University of Liverpool in the United Kingdom
https://www.hematologyadvisor.com/features/covid-amyloid-fibrin-micro-clots-central-treatment-risk/
How the Spike Protein Causes Amyloid “Clots” (and how to stop the clot)
https://rumble.com/vmlz42-funeral-director-john-olooney-blows-the-whistle-on-covid.html
https://www.youtube.com/watch?v=5x26445VcFo
https://www.youtube.com/watch?v=wwdRfbPrGIY
https://rumble.com/v1r2ts2–live-daily-show-louder-with-crowder.html?start=1031s
https://rumble.com/search/video?q=john%20o%27looney&sort=views§ion=sort
https://x.com/r_hirschman/status/1759337235042758748
https://rumble.com/v11qcta-unbelievable-blood-clots-video-from-embalmer-richard-hirschman.html
https://www.ntd.com/strange-new-blood-clots-in-most-bodies-embalmers_837378.html
https://www.youtube.com/watch?v=nLl69c46JK0
https://www.youtube.com/watch?v=-o20mtbsL7Q
https://www.youtube.com/watch?v=rz-TPhaOQN8
https://www.bitchute.com/search/?query=richard%20hirschman&kind=video
https://www.youtube.com/watch?v=4rAoqhTUU0g
https://www.youtube.com/watch?v=sVpFs2VTgf8
https://www.youtube.com/watch?v=PpCHP_ZU2HU
https://www.bitchute.com/video/97XZtGGKKs6M/
https://www.brighteon.com/5417b909-a765-421d-aee0-3ed502979fda
https://rumble.com/v4xejeh-died-suddenly-official-documentary-film.html
The SARS-CoV-2 spike protein is remarkably effective at disrupting many critical physiologic processes both in the short term and in the long term.
https://www.midwesterndoctor.com/p/what-is-causing-the-died-suddenly
Reviewing the results of a recent citizen’s investigation and what we now know about these amyloid clots.
https://www.midwesterndoctor.com/p/embalmers-are-continuing-to-find
https://www.youtube.com/watch?v=z06xBRCwGp0
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Originally Published: 2025-01-14 03:07:00
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